Samain R, Maiques O, Monger J, Lam H, Candido J, George S, Ferrari N, KohIhammer L, Lunetto S, Vilardell F, Olsina JJ, Matias-Guiu X, Sarker D, Biddle A, Balkwill FR, Eyles J, Wilkinson RW, Kocher HM, Calvo F, Wells CM, SanzMoreno V (2023)
CD73 controls Myosin II driven invasion, metastasis and immunosuppression in amoeboid pancreatic cancer cellsScience Advances


-Crosas-Molist E, Graziani V, Maiques O, Pandya P, Monger J, Samain R, George SL, Malik S, Salise J, Morales V, Le Guennec A, Atkinson RA, Marti RM, Matias-Guiu X, Charras G, Conte MR, Elosegui-Artola A, Holt M, Sanz-Moreno V (2023)
AMPK is a Mechano-Metabolic Sensor Linking Mitochondrial Dynamics to Myosin II Dependent Cell Migration.
Nature Communications
-Jung-Garcia Y, Maiques O, Monger J, Rodriguez-Hernandez I, Fanshawe B, Domart MC, Renshaw M, Marti RS, Matias-Guiu X, Collinson LM, Sanz-Moreno V* & Carlton JG* (2023)
*co-corresponding and co-senior authors, equal contribution.
LAP1 regulates nuclear plasticity to enable melanoma constrained migration and invasion.
Nature Cell Biology

-George S, Martin JA, Graziani V and Sanz-Moreno V (2023)
Amoeboid migration in health and disease: immune responses vs cancer dissemination.
Frontiers of Cell and Developmental Biology

-Barcelo J, Samain R and Sanz-Moreno V (2023)
Clinical utility of ROCK inhibitors in cancer.
Trends in Cancer


-Maiques O and Sanz-Moreno V (2022)
Multiplex chromogenic immunohistochemistry to stain and analyse paraffin tissue sections from the mouse or human.
Star Protocols

-Barcelo J and Sanz-Moreno V (2022) NECTIN1 is a melanoma metastasis suppressor gene.
Nature Genetics

-George S, Georgouli M and Sanz-Moreno V (2022) Protocol to drive human monocyte-to-macrophage polarization in vitro using tumor conditioned media.

Star Protocols :

-Adams R, Osborn, Mukhia B, Laddach R, Willsmore Z, Chenoweth A, Geh JLC, MacKenzie-Ross A, Healy C, Barber L, Tsoka S, Sanz-Moreno V, Lacy KE, Karagiannis SN. Influencing tumour-associated macrophages in malignant melanoma with monoclonal antibodies

OncoImmunology :

Perdrix-Rosell A, Maiques O, Martin JA, Chakravarty P, Ombrato L, Sanz Moreno V*, Malanchi I* (2022) Early functional mismatch between breast cancer cells and their tumour microenvironment suppresses long term growth. *co-corresponding co-senior authors.
Cancer Letters

-Roy-Luzarraga M, Reynolds LE, Luxán-Delgado B, Maiques O, Wisniewski L, Newport E, Rajeeve V, Drake RGJ, Gómez-Escudero J, Richards FM, Weller C, Dormann C, Meng YM, Vermeulen PB, Saur D, Sanz-Moreno V, Wong PP, Géraud C, Cutillas PR, Hodivala-Dilke K (2022) Low endothelial cell FAK expression reduces pancreatic ductal adenocarcinoma liver metastasis after gemcitabine treatment
Cancer Research doi: 10.1158/0008-5472.CAN-20-3807

-Graziani V, Rodriguez-Hernandez I, Maiques O and Sanz-Moreno V (2022)
The amoeboid state as part of the epithelial to mesenchymal transition program.
Trends in Cell Biology.
Our article made it to the cover of the March 2022 issue

-Crosas-Molist E, Samain R, Kohlhammer L, Orgaz JL, George SL, Barcelo J, Maiques O, Sanz-Moreno V (2021)
Rho GTPase signalling in Cancer Progression and Dissemination
Physiological Reviews
Our article made it to the cover of the January 2022 issue.


-De Winde CM, George SL, Arp AB, Benjamin AC, Crosas-Molist E, Hari-Gupta Y, Carver A, Imperatore V, Martinez VG, Sanz-Moreno V, Acton SE (2021)
Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

-Candido J*, Maiques O*, Boxberg M, Kast V, Peerani E, Tomas Bort E, Weichert W, Sananes A, Papo N, Magdolen V, Sanz-Moreno V, Loessner D (2021)
Kallikrein-related peptidase 6 is a potential therapeutic target in pancreatic ductal adenocarcinoma. *equal contribution

-Maiques O, Sanz-Moreno V (2021)
Location, location, location: melanoma cells “living at the edge”
Experimental Dermatology

Maiques O, Fanshawe B, Rodriguez-Hernandez I, Volpe A, Crosas Molist E, Cantelli G, Boehme L, Orgaz JL, Mardakheh F, Sanz-Moreno V* , Fruhwirth G* (2021) A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma.
*co-corresponding co-senior authors
British Journal of Cancer.


-Rodriguez-Hernandez I, Maiques O, Cantelli G, Perdrix A, Monger J, Fanshawe B, Karagiannis S, Santacana M, Mathias Guiu X, Maria Marti R, Orgaz JL, Fruhwirth G, Malanchi I, Sanz-Moreno V (2020) WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion
Nature Communications.

-Farrugia AJ, Rodríguez J, Orgaz JL, Lucas M, Sanz-Moreno V, Calvo F. Cdc42EP5/BORG3 coordinates septin and actin networks to promote actomyosin function and melanoma invasion and metastasis (2020)
Journal Cell Biology

-McLeod R, Kumar R, Papadatos-Pastos D, Mateo J, Brown JS, Ingles Garces AH, Ruddle R, Decordova S, Jueliger S, Ferraldeschi R, Maiques O, Sanz-Moreno V, Jones P, Traub S, Halbert G, Mellor S, Swales KE, Raynaud FI, Garrett MD and Banerji U. First-in-human study of AT13148, a dual ROCK-AKT inhibitor in patients with solid tumors.
Clinical Cancer Research

-Wong PP, Muñoz-Félix JM, Hijazi M, Kim H, Robinson S, de Luxan-Delgado B, Rodriguez-Hernandez I, Maiques O, Meng Y-M, Meng Q, Bodrug N, Dukinfield MS, Reynolds LE, Elia G, Clear A, Harwood C, Wang Y, Campbell JJ, Singh R, Zhang P, Schall TJ, Matchett KP, Henderson NC, Szlosarek PW, Dreger SA, Smith S, Jones LJ, Gribben JG, Cutillas P, Meier P, Sanz-Moreno V and Hodivala-Dilke KM (2020) Cancer burden is controlled by mural cell-beta3-integrin regulated crosstalk with tumor cells

-Orgaz JL, Crosas-Molist E, Sadok A, Perdrix-Rosell A, Maiques O, Monger J, Rodriguez-Hernandez I, Mele S, Georgouli M, Bridgeman V, Karagiannis P, Pandya P, Cantelli G, Boehme L, Wallberg F, V Tape C, Karagiannis SN, Malanchi I, Sanz-Moreno V (2020) Myosin II reactivation and Cytoskeletal remodelling as a hallmark and a vulnerability in melanoma resistance.
Cancer Cell, 37, 85-103.

Samain R and SanzMoreno V (2020) Cancer‐associated fibroblasts: activin A adds another string to their bow
Embo Molecular Medicine

Orgaz JL and Sanz-Moreno V (2020). What does not kill you makes you stronger: surviving anti-cancer therapies by cytoskeletal remodeling and Myosin II reactivation
Molecular & Cellular Oncology


-Foxall E, Staszowska A, Hirvonen L, Georgouli M, Ciccioli MC, Rimmer A, Calle Y, Sanz-Moreno V, Cox S. Jones GE, Wells CM (2019) PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells.
Cell Reports

-Maiques O, Georgouli M, Sanz-Moreno V (2019) Recent advances in tissue imaging for cancer research. F1000 Research

-Rosel D, Fernandes M, Sanz-Moreno V and Brábek J (2019) Migrastatics: Redirecting R&D in Solid Cancer Towards Metastasis? Trends in Cancer

-Valcarcel-Jimenez L, Macchia A, Crosas-Molist E, Schaub-Clerigué A, Camacho L, Martín-Martín N, Cicogna P, Viera-Bardón C, Fernández-Ruiz S, Rodriguez-Hernandez I, Hermanova I, Astobiza I, Cortazar AR, Corres-Mendizabal J, Gomez-Muñoz A, Sanz-Moreno V, Torrano V, Carracedo A. (2019) PGC1α suppresses prostate cancer cell invasion through ERRα transcriptional control. Cancer Res. doi: 10.1158/0008-5472

-López-Luque J, Bertran E, Crosas-Molist E, Maiques O, Caballero-Díaz D, Malfettone A, Caja L, Addante A, Sánchez A, Herrera B, Serrano T, Ramos E, Sanz-Moreno V* &, Fabregat I* (2019). Loss of EGFR in hepatocellular carcinoma facilitates TGF-β induced epithelial to amoeboid transition.Cancer Lett 464:15-24. doi:10.1016/j.canlet.2019.08.011. *co-senior authors.

-Dukinfield M, Maniati E, Reynolds L, Aubdool A, Baliga R, D’Amico G, Maiques O, Wang J, Bedi K, Margulies K,Sanz-Moreno V, Hobbs A, Hodivala-Dilke K. Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease.Journal of Pathology. doi: 10.1002/path.5340.

-Georgouli M, Herraiz C, Crosas-Molist E, Fanshawe B, Maiques O, Perdrix A, Pandya P, Cantelli G, Rodriguez-Hernandez I, Karagiannis P, Lam H, Josephs D, Matias-Guiu X, Marti RM, Nestle FO, Orgaz JL, Malanchi I, Fruhwirth GO, Karagiannis SN and Sanz-Moreno V (2019) Regional activation of Myosin II in cancer cells drives tumour progression via a secretory cross-talk with the immune microenvironment. Cell. Published: January 31, 2019. DOI:


Sanz-Moreno V and Balkwill FR (2018) Mets and NETs: The Awakening Force. Immunity. 49(5):798-800. doi: 10.1016/j.immuni.2018.11.009.

-Muliaditan T, Okesola M, Caron J, Georgouli M, Gordon P, Lall S, Kuzeva D, Pedro L, Shields J, Gillettn C, Diebold S, Sanz-Moreno V, Ng T, Hoste E, Arnold J (2018) Tumour-associated macrophages exploit an innate wound healing response to facilitate metastasis. Nat Comm. 9(1):2951. doi: 10.1038/s41467-018-05346-7.

Victoria Sanz-Moreno. People and ideas (2018) J Cell Biol.

-Villaronga MA, Hermida-Prado F, Granda-Díaz R, Menéndez ST, Álvarez-Teijeiro S, Quer M, Vilaseca I, Allonca E, Garzón E, Sanz-Moreno V, Astudillo A, Rodrigo JP, García-Pedrero JM. (2018) Immunohistochemical expression of cortactin and focal adhesion kinase predicts recurrence risk and laryngeal cancer risk beyond histological grading. In press, Cancer Epidemiology, Biomarkers & Prevention. doi: 10.1158/1055-9965.EPI-17-1082

-Maiques O, Barceló C, Panosa A, Pijuan J, Orgaz JL, Rodriguez-Hernandez I, Matas C, Vilella R, Fabra A, Puig S, Sanz-Moreno V, Matias-Guiu X, Canti C, Herreros J, Marti RM, Macià A (2018) T-type calcium channel blockers inhibit autophagy and reduce migration/invasion in BRAFV600E melanoma cells through Snail1 expression.Pigment Cell and Melanoma Res. doi: 10.1111/pcmr.12690.

-Villaronga MÁ, Teijeiro SÁ, Hermida-Prado F, Garzón-Arango M, Sanz-Moreno V, García-Pedrero JM. (2018) Analysis of Invasive Activity of CAF Spheroids into Three-Dimensional (3D) Collagen Matrices. Methods Mol Biol; 1731:145-154. doi: 10.1007/978-1-4939-7595-2_14.


-Pandya P, Orgaz JL and Sanz-Moreno V (2017)
Actomyosin contractility in collective migration: May the force be with you. Special issue on “Cell Dynamics”
Curr Opin Cell Biol, 48:87–96

-Gandalovičová A, Rosel D, Fernandes M, Veselý P, Heneberg P, Čermák V, Petruželka L, Kumar S, Sanz-Moreno V *and Brábek J* (2017) *co-corresponding authors MIGRASTATICS, the anti-metastatic and anti-invasion drugs: the promise and challenges. Trends in Cancer,3(6):391-406

-Orgaz and Sanz-Moreno V (2017)
IBook Chapter on RhoA. Encyclopedia of Signaling Molecules. Springer. DOI10.1007/978-1- 4614-6438-9_101793-1

-Victoria Sanz-Moreno: Cell scientist to watch. (2017) Featured J Cell Sci. 130(7):1199-1200

-Orgaz JL, Pandya P and Sanz-Moreno V (2017)
Modes of cell migration during cancer invasion and metastasis. In press, Molecular Oncology. 10.1002/1878-0261.12019.

-Krupina K, Kleiss C, Rodriguez-Hernandez I, Sanz-Moreno V and Sumara I (2017).
UBASH3B-mediated silencing of the mitotic checkpoint: therapeutic perspectives in cancer cells. Molecular & Cellular Oncology, 10.1080/23723556.2016.1271494

-Josephs D, Bax H , Dodev T , Georgouli M, Nakamura M, Pellizzari G, Saul L , Karagiannis P , Cheung A, Herraiz C, Ilieva K, Correa I, Fittall M, Crescioli S, Gazinska P, Woodman N, Mele S , Chiaruttini G, Gilbert A, Dr. Koers A, Bracher M, Selkirk C, Lentfer H, Barton C, Lever E, Muirhead G, Tsoka S, Canevari S, Figini M, Montes A, Downes N, Dombrowicz D, Corrigan C,. Beavil AJ, Nestle FO, Jones p, Gould H, Sanz-Moreno V, Blower P, Spicer J, Karagiannis S (2017)
IgE cancer immunotherapy is mediated by macrophage polarization via a TNFα/MCP-1 axis.
Cancer Res. doi: 10.1158/0008-5472.

-Crosas E, Bertran E, Cantelli G, Herraiz C, Rodriguez-Hernandez I, Fabra A, Sanz-Moreno V* and Fabregat I* (2017) *co-corresponding senior authors
NADPH oxidase 4 represses Epithelial to Amoeboid transition and efficient tumour dissemination. Oncogene. doi: 10.1038/onc.2016.454